Corifollitropin alfa
Elonva (corifollitropin alfa) is a protein pharmaceutical. Corifollitropin alfa was first approved as Elonva on 2010-01-25. It has been approved in Europe to treat assisted reproductive techniques, investigative techniques, and ovulation induction.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| therapeutics | D013812 |
| investigative techniques | D008919 |
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Abbreviated New Drug Application (ANDA)
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Agency Specific
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Clinical
Clinical Trials
71 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infertility | D007246 | EFO_0000545 | — | 3 | 6 | 9 | 13 | 12 | 42 |
| Female infertility | D007247 | EFO_0008560 | N97 | — | — | 1 | 2 | 7 | 10 |
| Fertilization in vitro | D005307 | — | — | — | 2 | 2 | 1 | 2 | 7 |
| Ovulation induction | D010062 | — | — | — | 1 | — | 2 | — | 3 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | 1 | — | 1 |
| Ovarian reserve | D065851 | EFO_0004770 | — | — | — | — | 1 | — | 1 |
| Oocyte donation | D018587 | — | — | — | — | — | 1 | — | 1 |
| Preimplantation diagnosis | D019836 | — | — | — | — | — | 1 | — | 1 |
| Fertility preservation | D059247 | — | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypogonadism | D007006 | — | E23.0 | — | — | 2 | — | — | 2 |
| Helping behavior | D006379 | — | — | — | — | 2 | — | — | 2 |
| Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | — | — | 1 | — | — | 1 |
| Fertility | D005298 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fertilization | D005306 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | — | — | 7 | 7 |
| Primary ovarian insufficiency | D016649 | EFO_0004266 | E28.3 | — | — | — | — | 1 | 1 |
| Premature menopause | D008594 | — | E28.31 | — | — | — | — | 1 | 1 |
| Congenital abnormalities | D000013 | EFO_0003915 | Q89.9 | — | — | — | — | 1 | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | — | — | 1 | 1 |
| Male breast neoplasms | D018567 | — | — | — | — | — | — | 1 | 1 |
| Female genital diseases | D005831 | EFO_0009549 | N85 | — | — | — | — | 1 | 1 |
| Healthy volunteers/patients | — | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Corifollitropin alfa |
| INN | corifollitropin alfa |
| Description | Gonadotropin preparations are drugs that mimic the physiological effects of gonadotropins, used therapeutically mainly as fertility medication for ovarian hyperstimulation and ovulation induction. For example, the so-called menotropins consist of LH and FSH extracted from human urine from menopausal women. There are also recombinant variants.
|
| Classification | Protein |
| Drug class | tricyclic compounds; atropine derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108185 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | T7K20Y2GWY (ChemIDplus, GSRS) |
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Safety
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70 adverse events reported
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